8 Arm Exercises You Haven’t Done Before + MORE

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U.S. Scientists Use CRISPR to Fix Genetic Disease in Human Embryos For the First Time

– www.health.com

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This article originally appeared on Time.com.

Scientists have successfully used CRISPR, a tool that cuts DNA with more precision than any other genome editing technology, to fix a genetic defect in human embryos that can cause serious heart problems, according to a landmark new study in the journal Nature. This is the first use of CRISPR on human embryos in the U.S.

Chinese scientists have reported using CRISPR to correct genetic defects in human embryos, but some of the embryos they used weren’t viable.

Shoukhrat Mitalipov, from Oregon Health & Science University, collaborated with researchers at the Salk Institute, as well as with scientists from China and South Korea, to improve on those results. They applied CRISPR at the earliest stage possible—when the embryo is still a single cell—to ensure that the genetic changes they introduced were propagated to every cell of the embryo as it divided and developed. Because the embryos were created for research purposes only, none were allowed to develop beyond three days.

MORE: First CRISPR Human Trial Approved in the U.S.

CRISPR, which was introduced in 2012, precisely cuts DNA but does not repair it. If combined with other techniques, however, researchers say it could both cut out disease-causing genes and replace them with healthy versions to essentially cure genetic human diseases. So in order to further the science, Mitalipov and his colleagues wanted to test what happened when CRISPR was used in a human embryo. Theoretically, once CRISPR broke the DNA in the appropriate place to cut out a mutation, the cell’s natural repair mechanisms would kick in to repair the injury, fixing the defect this time with the proper code—much like how a word processor’s autocorrect function fixes spelling mistakes.

Unfortunately, this process isn’t very efficient in adult cells in which CRISPR has been tested, so Mitalipov expected similarly low yields in the embryos.

To his surprise, however, he found that embryos were very effective at fixing breaks in DNA.

He created embryos that contained a specific defect known to cause a heart condition by fertilizing healthy donor eggs from various women with sperm from a man who carried the genetic mutation for the disease. He then introduced CRISPR to splice out the mutated gene in more than 50 embryos just after the sperm fertilized the eggs, when the embryos were still just one cell. Several days later, 72% of the embryos showed no sign of the mutated gene; the gene was essentially corrected in all of their cells.

MORE: How the Science of CRISPR Can Change Your Genes

It turns out that the embryo relies on the normal copy of the gene, in this case from the egg, to fix the break made when CRISPR cut out the mutated gene. They key was to introduce CRISPR early enough so the embryo’s own DNA repair system could fix the mutated gene. That’s encouraging for one potential use of CRISPR in the future as a way to correct inherited genetic disease, says Mitalipov, since the embryo seems to have a built-in, reliable way of repairing the injury caused by splicing out an abnormal gene…

Chrissy Teigen Got Super Real About Her 'Period Skin' Pimples on Snapchat

– health.com

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This article originally appeared on People.com.

No matter the situation, Chrissy Teigen isn’t afraid to speak her mind. The star’s honest, tell-it-like-it-is attitude even got her blocked by President Donald Trump on Twitter after she told him, “no one likes you.” (Don’t worry, Teigen was “so happy” Trump blocked her.)

Besides opening up about her political point of view, Teigen keeps it real by sharing her most hilarious and sometimes even cringe-worthy confessions with her fans. Whether she reveals all the intimate details about her sex life with husband John Legend or that she prefers to go commando, we can always count on the model for her blunt candor and advice.

Monday night, Teigen shared what may possibly be her most relatable female dilemma with her fans on Snapchat: the misery of “period skin.”

RELATED PHOTOS: Editors’ Picks: The Best Concealers We Always Have in Our Makeup Bags!

Almost everyone has experienced those pesky hormonal breakouts, but it isn’t often you see big time stars like Teigen showing their pimples to the world without any concealer.

“This is my skin on my period,” Teigen said, displaying her barefaced skin with blemishes on her nose, chin and forehead. “So angry.”

We feel you, Chrissy. But don’t worry: We did some digging and rounded up the best solutions to zap those period pimples and conceal them at the same time. Check them out below!

One dab of this full-coverage concealer, which is formulated to work best with acne prone skin, will erase any flaws and imperfections.

Buy It: IT Cosmetics Bye Bye Breakout Full-Coverage Treatment Concealer, $28; itcosmetics.com

Sip on this yummy doctor-developed beauty supplement (it can be mixed with your morning coffee, tea or smoothie) during the first five days of your cycle to keep skin clear and radiant.

Buy It: BeautyMe The One, $19.95; beautyme.shop

This concealer doesn’t just cover pimples — it’s medicated with a gentle formula that actually heals blemishes too!

Buy It: Clinique Acne Solutions Clearing Concealer, $18; sephora.com

8 Arm Exercises You Haven’t Done Before

– health.com

8 Arm Exercises You Haven’t Done Before

You can read the rest of this article on Life by Daily Burn.

You’ve probably cranked out a bunch of bicep curls and triceps kickbacks throughout your days at the gym. And while these moves work great for building muscles in your upper body, a few creative takes on your typical arm workout will help you carve even better results. That’s especially true if the exercises mix a few movements into one, so you work more muscles simultaneously (that means you’ll burn more calories, too). Enter: These eight creative arm exercises you probably haven’t tried before.

When you say you want sculpted bis, tris, shoulders and back muscles — we say master these moves. Flex it out with this ultimate upper body workout.

RELATED: 3 Quick Triceps Exercises for Sculpted Arms

8 Arm Exercises for a Better Upper Body Workout

Perform each exercise below, in order, for 30 seconds each. Try to eliminate rest time between each move. After the eighth exercise, take a 60-second breather, then repeat two more times. To really intensify the strengthening power, pick up a pair of dumbbells. Soon you’ll want to bare those arms all the time.

GIFs: Daily Burn 365

1. Bicep Curl in Stationary Bear Crawl

Show off your guns by working your biceps (the front of your arm) from a different angle than the standard palm-forward posture. While you do it, you’ll be chiseling your core thanks to the stability-testing stance.

How to: Start on your hands and knees, wrists under shoulders and knees under hips (a). Lift your knees an inch or two off the ground and hold them there, back flat and abs tight (b). Turning your palm up and elbow out to the side, bend your right elbow, curling your hand up to your chest. Your right arm should be perpendicular to your left (c). Place your right hand back down and repeat on the left side (d). Continue alternating.

2. Tricep Chop

You’ll strengthen the back of your arms, aka your triceps, as you perfect this rotational chop. Consider your obliques toned, too.

How to: Start standing with feet hip-width apart, slight bend in your knees (a). Clasp your hands together (or hold a dumbbell on both sides) and bring them to your left side, turning your shoulders and head to the left. Your hips should stay facing forward (b). Then, swiftly move your hands overhead, straightening your arms (c). Bend at the elbows to bring your hands behind your head. Keep your elbows squeezing in close to your ears (d). Straighten your arms back overhead (e). Next, bring your hands down to your right side, twisting your upper body to the right (f). Return to the tricep extension and repeat, as you continue alternating sides for the chop.

RELATED: More Muscle, Please: The Evolution of Women’s Arms

3. Hinged Front Raise to Reverse Fly

Welcome a chiseled back and shoulders with this two-for-one move…

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U.S. Scientists Use CRISPR to Fix Genetic Disease in Human Embryos For the First Timewww.health.com
Chrissy Teigen Got Super Real About Her 'Period Skin' Pimples on Snapchathealth.com
8 Arm Exercises You Haven’t Done Beforehealth.com

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